Endothelial Cell DNA Integrity following Anoxia/Reoxygenation Injury
نویسندگان
چکیده
منابع مشابه
CORRELATION BE TWEEN ENDOTHELIAL INJURY AND CEREBRAL VASOSPASM FOLLOWING A DOUBLE SUBARACHNOID HEMORRHAGE IN THE RAT
While a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (SAH), the most consistent is endothelial damage. Since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following SAH. This experimental study investigates the correlation between end...
متن کاملEndothelial repair following Nd:YAG laser injury.
Effects of different energy levels (1.2, 2.0, 2.8, 4.0 mj) of a mode-locked Nd:YAG laser beam focused directly on the corneal endothelium were evaluated in rabbit, cat, and owl monkey. The endothelial lesion observed by specular microscopy at 10 min; 8, 16, and 24 hr; 3, 5, 7, and 21 days measured up to 0.8 mM in diameter. It showed focal destruction of Descemet's membrane and a larger area of ...
متن کاملStructural and functional vocal fold epithelial integrity following injury.
OBJECTIVES/HYPOTHESIS An intact epithelium is an important part of vocal fold defense. Damage to the epithelium can compromise vocal fold homeostasis and protection of the host tissue from viral and bacterial invasion. Elucidating the effects of damage on epithelial architectural and barrier integrity provides insight into the role of epithelium in protecting vocal folds. Using an animal model,...
متن کاملAxonal integrity predicts cortical reorganisation following cervical injury
BACKGROUND Traumatic spinal cord injury (SCI) leads to disruption of axonal architecture and macroscopic tissue loss with impaired information flow between the brain and spinal cord-the presumed basis of ensuing clinical impairment. OBJECTIVE The authors used a clinically viable, multimodal MRI protocol to quantify the axonal integrity of the cranial corticospinal tract (CST) and to establish...
متن کاملEndothelial cell seeding influences lesion development following arterial injury in the cholesterol-fed rabbit.
OBJECTIVE A functionally intact endothelial monolayer is thought to be critical for the adaptive process of vascular remodeling. This study was undertaken to examine the hypothesis that endothelial restoration is a critical determinant of remodeling after balloon angioplasty. METHODS Rabbits (N=12) were fed a cholesterol-supplemented diet (0.5%) and were subjected to bilateral balloon cathete...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2016
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.30.1_supplement.985.1